Manufacturer:

          Novartis Pharma

Contents:

          Diclofenac Na

Indications:

          Enteric-coated tab/SR tab/IM inj/Supp Inflammatory & degenerative forms of rheumatism. Post-traumatic & post-op pain, inflammation & swelling. Enteric-coated tab/IM inj/Supp Acute gout. Enteric-coated tab/SR tab/Supp Painful &/or inflammatory conditions in gynaecology. Enteric-coated tab/Supp Adjuvant in severe painful inflammatory infections of the ENT. Juvenile RA. IM inj/Supp Migraine attacks. IM inj Renal & biliary colic. IV infusion Treatment or prevention of post-op pain in a hospital setting.

Contraindications:

          Active gastric or intestinal ulcer, bleeding or perforation. Severe hepatic, renal & cardiac failure. Patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid &/or other drugs w/ prostaglandin synthetase inhibitory activity. Treatment of peri-op pain in setting of coronary artery bypass graft (CABG) surgery. Pregnancy (last trimester) & lactation. Inj Hypersensitivity to Na metabisulphite. Supp Proctitis.

Special Precautions:

          May mask the signs & symptoms of infections or temporarily inhibit platelet aggregation. Concomitant use w/ systemic NSAIDs & selective COX-2 inhibitors. Symptoms of GI disorders or w/ history of gastric or intestinal ulceration, bleeding or perforation. Ulcerative colitis or Crohn's disease. Preexisting asthma, hepatic porphyria, haemostasis defects. Impaired hepatic, renal & cardiac function, history of HTN, substantial extracellular vol depletion. Monitor hepatic & renal function, & blood counts (in prolonged treatment). May impair female fertility & ability to drive or operate machinery. Pregnancy (1st 2 trimesters). Elderly. Enteric-coated tab Rare hereditary problems of galactose intolerance, severe lactase deficiency or glucose-galactose malabsorption. SR tab Rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency. SR tab/Inj Not suitable for childn & adolescents. Inj Do not administer for >2 days or as IV bolus inj.

Dosage:

          Enteric-coated tab Adult Initially 100-150 mg daily. Mild/long-term therapy 75-100 mg daily. Total daily dose should be in 2-3 divided doses. Primary dysmenorrhoea 50-150 mg. Max: 200 mg/day. Adolescent/childn ≥1 yr 0.5-2 mg/kg body wt/day in 2-3 divided doses. Juvenille RA Up to 3 mg/kg body wt/day in divided doses. SR tab Adult Initially 100-150 mg daily. Mild/long-term therapy 75-100 mg daily. Take in the evening when symptoms are more pronounced in the morning/evening. IM inj Adult One 75-mg amp daily via deep intragluteal inj into the upper quadrant. Severe cases (eg colic) May increase dose to two 75-mg amp w/ a few hr interval or one 75-mg amp may be combined w/ other dosage forms (eg tab, supp) up to a max of 150 mg daily. Migraine attacks One 75-mg amp followed by 100-mg supp if required. Max: 175 mg daily on the 1st day. IV infusion Moderate to severe post-op pain 75 mg infused continuously over 30 min-2 hr. Max: 150 mg/24 hr. Prevention of post-op pain Loading dose: 25-50 mg infused after surgery over 15 min-1 hr followed by continuous infusion of 5 mg hrly. Max: 150 mg daily. Supp Adult Initially 100-150 mg daily. Mild/long-term therapy 75-100 mg daily. Total daily dose should be in 2-3 divided doses. Suppression of nocturnal pain & morning stiffness Up to a max of 150 mg. Primary dysmenorrhoea 50-150 mg. Max: 200 mg/day. Migraine attacks Starting dose: 100 mg. Max: 150 mg daily in divided doses. Adolescent/childn ≥1 yr 0.5-2 mg/kg body wt daily in 2-3 divided doses. Juvenile RA Up to 3 mg/kg daily in divided doses.

Class:

          Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

Presentation/Packing:

           Voltaren 25 mg x 100's. Voltaren 50 mg x 10's. Voltaren 75 mg x 10's. Voltaren 75 mg/3 ml x 1 box x 5 tubes

Details:

          MyPhuocPharmacy – (08) 62581003